| Identification | Back Directory | [Name]
Tacrolimus Impurity 26 | [CAS]
104987-25-9 | [Synonyms]
Tacrolimus Impurity 26
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-[2-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-methoxycyclohexyl]-1-methylethenyl]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, [3... | [Molecular Formula]
C50H83NO12Si | [Molecular Weight]
918.28 |
| Chemical Properties | Back Directory | [Boiling point ]
880.0±75.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [solubility ]
soluble in Chloroform, Dichloromethane, Ethyl Acetate | [form ]
Solid | [pka]
9.97±0.70(Predicted) | [color ]
Off-white |
| Hazard Information | Back Directory | [Uses]
33-tert-Butyldimethylsilyloxy-FK 506 is an intermediate in the synthesis of Iso-FK-506 (iso-Tacrolimus) (I816250), which is an isomer of FK-506 (F370000) from fermentation of Streptomyces tsukubaensis, as immunosuppressant and antiinflammatory agent. |
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