| Identification | Back Directory | [Name]
Ro 51 | [CAS]
1050670-85-3 | [Synonyms]
Ro 51
2-((4-Amino-5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidin-2-yl)amino)propane-1,3-diol
2-[[4-amino-5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidin-2-yl]amino]propane-1,3-diol
2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2-pyrimidinyl]amino]-1,3-propanediol
1,3-Propanediol,2-[[4-amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2-pyrimidinyl]amino]-
2-[[4-Amino-5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinyl]amino]-1,3-propanediol | [Molecular Formula]
C17H23IN4O4 | [MOL File]
1050670-85-3.mol | [Molecular Weight]
474.29 |
| Hazard Information | Back Directory | [Uses]
Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3. P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a pot
ential option in the treatment of pain. | [Uses]
Ro 51 is a potent and selective dual antagonist of purinoceptor subtypes P2X3 and P2X2/3. P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions making Ro 51 a potential option in the treatment of pain. | [in vivo]
Ro-51 suffers rapid clearance, short half-lives, and high protein binding in rat[1].
| Animal Model: | Rat[1] | | Dosage: | 2 mg/kg (Pharmacokinetic Analysis) | | Administration: | Oral administration | | Result: | AUC= 237 ng/h/mL, T 1/2 =1.52 h |
| [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Alomone Labs
|
| Tel: |
4008-168-068 13121892008 |
| Website: |
www.alomone.com |
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