ChemicalBook--->CAS DataBase List--->1054624-77-9

1054624-77-9

1054624-77-9 Structure

1054624-77-9 Structure
IdentificationBack Directory
[Name]

Ranolazine-d3
[CAS]

1054624-77-9
[Synonyms]

RS 43285-d3
Ranolazine-d3
RS 43285-193-d3
N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxy-d3-phenoxy)propyl]-1-piperazineacetamide
N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-[2-(methoxy-d3)phenoxy]propyl]-1-piperazineacetamide
[Molecular Formula]

C24H33N3O4
[MOL File]

1054624-77-9.mol
[Molecular Weight]

427.537
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

113-1160C
[storage temp. ]

-20?C Freezer
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White
[InChI]

InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29)
[InChIKey]

XKLMZUWKNUAPSZ-UHFFFAOYSA-N
[SMILES]

c1cc(OCC(O)CN2CCN(CC(=O)Nc3c(C)cccc3C)CC2)c(OC)cc1
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Labeled Ranolazine, intended for use as an internal standard for the quantification of Ranolazine by GC- or LC-mass spectrometry.
[Uses]

Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Antianginal.
[Physiological effects]

Ranolazine-d3 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. 
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