| Identification | Back Directory | [Name]
5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE | [CAS]
105659-32-3 | [Synonyms]
2',3',5'-Triacetyl-5-bromouridine
2,3,5-Tri-O-acetyl-5-bromouridine
5-bromouridine 2',3',5'-Triacetate
5-BROMO-2',3',5'-TRI-O-ACETYLURIDINE
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate | [Molecular Formula]
C15H17BrN2O9 | [MDL Number]
MFCD01318090 | [MOL File]
105659-32-3.mol | [Molecular Weight]
449.21 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
5-Bromo-2',3',5'-tri-O-acetyluridine diacetate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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