Identification | Back Directory | [Name]
B-SITOSTENONE | [CAS]
1058-61-3 | [Synonyms]
Nsc 49082 Sitostene B-SITOSTENONE Stigmastenone β-Sitostenone BETA-SITOSTENONE 4-Stigmasten-3-one SITOSTENONE, BETA- 3-Keto-β-cytostenol STIGMAST-4-EN-3-ONE beta-Rosasterol oxide beta-Sitost-4-en-3-one 3-Oxo-Δ4,5-sitosterone SINOMENINE HYDROCHLORIDE (RG) Stigmast-4-en-3-one (8ci)(9ci) (24R)-24-Ethylcholest-4-en-3-one | [Molecular Formula]
C29H48O | [MDL Number]
MFCD00200560 | [MOL File]
1058-61-3.mol | [Molecular Weight]
412.69 |
Chemical Properties | Back Directory | [Melting point ]
82 °C(Solv: methanol (67-56-1)) | [Boiling point ]
503.8±17.0 °C(Predicted) | [density ]
0.97±0.1 g/cm3(Predicted) | [solubility ]
DMF: 0.33 mg/ml Ethanol: Slightly soluble | [form ]
Solid | [color ]
White to off-white | [LogP]
10.240 (est) | [EPA Substance Registry System]
Stigmast-4-en-3-one (1058-61-3) |
Hazard Information | Back Directory | [Uses]
β-Sitostenone is a sterols that can be isolated from Cochlospermum vitifolium.β-Sitostenone inhibits tyrosinase activity, and has anti-melanogenic and anti-tumor activities[1][2][3]. | [Definition]
ChEBI:Beta-sitostenone is a steroid and a C29-steroid. It has a role as a metabolite. It derives from a hydride of a stigmastane. | [IC 50]
Human Endogenous Metabolite | [References]
[1] Aguilar-Guadarrama AB, et al. Flavonoids, Sterols and Lignans from Cochlospermum vitifolium and Their Relationship with Its Liver Activity. Molecules. 2018 Aug 5;23(8):1952. DOI:10.3390/molecules23081952 [2] Chu CW, et al. Biofunctional Constituents from Michelia compressa var. lanyuensis with Anti-Melanogenic Properties. Molecules. 2015 Jul 3;20(7):12166-74. DOI:10.3390/molecules200712166 [3] Fan SQ, et al. Sarocladione, a unique 5,10:8,9-diseco-steroid from the deep-sea-derived fungus Sarocladium kiliense. Org Biomol Chem. 2019 Jun 18;17(24):5925-5928. DOI:10.1039/c9ob01159e |
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