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1059677-23-4

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1059677-23-4 Structure

1059677-23-4 Structure
IdentificationBack Directory
[Name]

BPH715
[CAS]

1059677-23-4
[Synonyms]

BPH715
inhibit,Parasite,BPH-715,Inhibitor,BPH715,BPH 715
[Molecular Formula]

C17H31NO7P2
[MDL Number]

MFCD31813699
[MOL File]

1059677-23-4.mol
[Molecular Weight]

423.378
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

0.5 M NaOH : 80 mg/mL (188.96 mM; ultrasonic and adjust pH to 11 with NaOH)|DMSO : 5 mg/mL (11.81 mM; ultrasonic and warming and heat to 60°C)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells[1].
[References]

[1] Singh AP, et al. Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth. Antimicrob Agents Chemother. 2010 Jul;54(7):2987-93. DOI:10.1128/AAC.00198-10
Spectrum DetailBack Directory
[Spectrum Detail]

BPH715(1059677-23-4)1HNMR
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