| Identification | Back Directory | [Name]
Celecoxib iMpurity-G | [CAS]
1061214-06-9 | [Synonyms]
Celecoxib-5
Celecoxib-007
Celecoxib iMpurity-G
Celecoxib Related Compound D
(E)-4-(2-(1-(p-tolyl)ethylidene)
Celecoxib impurity A: Ketohydrazine condensation
4-(2-(1-p-tolylethylidene)hydrazinyl)benzenesulfonamide
(Z)-4-(2-(1-(p-tolyl)ethylidene)hydrazinyl)benzenesulfonamide
(E)-4-(2-(1-(p-tolyl)ethylidene)hydrazinyl)benzenesulfonamide
Benzenesulfonamide, 4-[2-[1-(4-methylphenyl)ethylidene]hydrazinyl]-
Celecoxib Impurity 1 ，4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfon | [Molecular Formula]
C15H17N3O2S | [MDL Number]
MFCD32214871 | [MOL File]
1061214-06-9.mol | [Molecular Weight]
303.38 |
| Chemical Properties | Back Directory | [Melting point ]
224-226 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
484.9±55.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | [form ]
Solid | [pka]
10.53±0.12(Predicted) | [color ]
White to Pale Yellow | [InChI]
InChI=1S/C15H17N3O2S/c1-11-3-5-13(6-4-11)12(2)17-18-14-7-9-15(10-8-14)21(16,19)20/h3-10,18H,1-2H3,(H2,16,19,20) | [InChIKey]
JCRSPJLUSHTDDS-UHFFFAOYSA-N | [SMILES]
C1(S(N)(=O)=O)=CC=C(NN=C(C2=CC=C(C)C=C2)C)C=C1 |
| Hazard Information | Back Directory | [Uses]
4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. |
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