| Identification | Back Directory | [Name]
Ethanone,1-(2-amino-4-pyrimidinyl)- | [CAS]
106157-82-8 | [Synonyms]
2-AMino-4-acetylpyriMidine
4-Acetyl-2-aminopyrimidine
1-(2-amino-4-pyrimidinyl)Ethanone
Ethanone,1-(2-amino-4-pyrimidinyl)-
1-(2-aminopyrimidin-4-yl)ethan-1-one
Ethanone, 1-(2-amino-4-pyrimidinyl)- (9CI) | [Molecular Formula]
C6H7N3O | [MDL Number]
MFCD09263814 | [MOL File]
106157-82-8.mol | [Molecular Weight]
137.14 |
| Chemical Properties | Back Directory | [Melting point ]
148-149 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
351.3±34.0 °C(Predicted) | [density ]
1.250±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [pka]
1.70±0.10(Predicted) | [Appearance]
Off-white to light brown Solid | [InChI]
InChI=1S/C6H7N3O/c1-4(10)5-2-3-8-6(7)9-5/h2-3H,1H3,(H2,7,8,9) | [InChIKey]
XDKSEDDZHXZRKQ-UHFFFAOYSA-N | [SMILES]
C(=O)(C1C=CN=C(N)N=1)C |
| Hazard Information | Back Directory | [Synthesis]
Using 4-(1,1-dimethoxyethyl)pyrimidin-2-amine (17.5 g, 95.5 mmol) as starting material, it was dissolved in formic acid and the reaction was stirred for 6 hours at room temperature. After completion of the reaction, the reaction solution was concentrated to dryness. The resulting residue was dissolved in ethanol (50 mL), stirred and filtered to obtain 1-(2-aminopyrimidin-4-yl)ethanone (9.2 g, 70% yield). | [References]
[1] Journal of Heterocyclic Chemistry, 1985, vol. 22, p. 1723 - 1726
[2] Patent: US2007/142415, 2007, A1. Location in patent: Page/Page column 17
[3] Patent: WO2005/14572, 2005, A1. Location in patent: Page/Page column 24; 25
[4] Patent: US2007/142414, 2007, A1. Location in patent: Page/Page column 19
[5] Patent: WO2007/96334, 2007, A1. Location in patent: Page/Page column 32-33 |
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| Company Name: |
Tcichem, Inc.
|
| Tel: |
13918644899 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19113/0_EN.htm |
| Company Name: |
BePharm Ltd
|
| Tel: |
400-685-9117 |
| Website: |
www.bepharm.com |
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