ChemicalBook--->CAS DataBase List--->106344-20-1

106344-20-1

106344-20-1 Structure

106344-20-1 Structure
IdentificationBack Directory
[Name]

tin mesoporphyrin
[CAS]

106344-20-1
[Synonyms]

Stannsoporfin
tin mesoporphyrin
Tin Mesoporphyrin IX (chloride)
Tin(IV) mesoporphyrin IX dichloride
[Molecular Formula]

C34H34Cl2N4O4Sn?2H
[MDL Number]

MFCD03425982
[MOL File]

106344-20-1.mol
[Molecular Weight]

753.29
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 1 mg/ml; DMSO: 0.5 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
[form ]

A crystalline solid
[color ]

Brown to reddish brown
[InChIKey]

LLDZJTIZVZFNCM-UHEVNVKKSA-J
[SMILES]

CC1=C(CCC(O)=O)/C2=C/C3=N/C(C(C)=C3CCC(O)=O)=C\C4=C(CC)C(C)=C(/C=C5N=C(C(C)=C\5CC)/C=C1\N26)N4[Sn]6(Cl)Cl
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Control of hyperbilirubinemia in preterm and term newborns (inhibitor of bilirubin).
[Brand name]

Stanate (Torcan).
[Biological Activity]

Stannsoporfin is a potent inhibitor of heme oxygenase 1 (HO-1) and heme oxygenase 2 (HO-2). It inhibits hepatic HO and controls serum levels of bilirubin in infants. Stannsoporfin potently inhibits myeloid HO-1 in tumors. It inhibits immune suppression of chemotherapy-elicited CD8+ T cells. Stannsoporfin concurrently administer with 5-Fluoro uracil produces immediate tumor regression in mice model of breast tumor.
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