| Identification | Back Directory | [Name]
epsilon-momfluorothrin | [CAS]
1065124-65-3 | [Synonyms]
ε-momfluorothrin
epsilon-momfluorothrin
Momfluorothrin, (Z,1R,3R)-
4-methoxymethyl-2,3,5,6-tetrafluorobenzyl (1R)-trans-3-((Z)-2-cyano-1-propenyl)-2,2-dimethylcyclopropane carboxylate
Cyclopropanecarboxylic acid, 3-[(1Z)-2-cyano-1-propen-1-yl]-2,2-dimethyl-, [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl ester, (1R,3R)- | [Molecular Formula]
C19H19F4NO3 | [MDL Number]
MFCD32062669 | [MOL File]
1065124-65-3.mol | [Molecular Weight]
385.35 |
| Chemical Properties | Back Directory | [Boiling point ]
403.0±45.0 °C(Predicted) | [density ]
1.321±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 5 mg/mL (12.98 mM) | [form ]
Solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Epsilon-momfluorothrin is a type I synthetic pyrethroid insecticide, activates constitutive androstane receptor (CAR), and induces hepatocellular tumors in rats[1]. | [Definition]
ChEBI: Epsilon-momfluorothrin is a carboxylic ester obtained by formal condensation between the carboxy group of (1R,3R)-3-[(1Z)-2-cyanoprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylic acid with the benzylic hydroxy group of [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methanol. It has a role as a pyrethroid ester insecticide and an agrochemical. It is a carboxylic ester, a member of cyclopropanes, an ether, an organofluorine insecticide, a tetrafluorobenzene and a nitrile. It is functionally related to a chrysanthemic acid. | [Production Methods]
Epsilon-momfluorothrin is synthesised commercially through a multi-step chemical process involving the esterification of a cyclopropane carboxylic acid derivative with a fluorinated benzyl alcohol | [Mechanism of action]
Axonic poison; keeps sodium channels in the neuronal membranes open, leading to hyperexcitation and paralysis. | [References]
[1] Okuda Y, et al. Editor's Highlight: Mode of Action Analysis for Rat Hepatocellular Tumors Produced by the Synthetic Pyrethroid Momfluorothrin: Evidence for Activation of the Constitutive Androstane Receptor and Mitogenicity in Rat Hepatocytes. Toxicol Sci. 2017 Aug 1;158(2):412-430. DOI:10.1093/toxsci/kfx102 | [Pesticide Type]
Insecticide |
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