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1065573-84-3

1065573-84-3 Structure

1065573-84-3 Structure
IdentificationBack Directory
[Name]

4-Quinolinol, 2-[[4-(2,2-dimethylpropyl)-3-(2-hydroxyethyl)-1-piperazinyl]methyl]-
[CAS]

1065573-84-3
[Synonyms]

2-((3-(2-hydroxyethyl)-4-neopentylpiperazin-1-yl)methyl)quinolin-4-ol
4-Quinolinol, 2-[[4-(2,2-dimethylpropyl)-3-(2-hydroxyethyl)-1-piperazinyl]methyl]-
[Molecular Formula]

C21H31N3O2
[MOL File]

1065573-84-3.mol
[Molecular Weight]

357.49
Chemical PropertiesBack Directory
[Boiling point ]

516.5±45.0 °C(Predicted)
[density ]

1.135±0.06 g/cm3(Predicted)
[pka]

4.47±0.40(Predicted)
Hazard InformationBack Directory
[Description]

KAL-21404358 is a Novel allosteric inhibitor of K-RasG12D, binding to the P110 site of K-RasG12D, impairing the K-RasG12D interaction with B-Raf, and disrupting the RAF-MEK-ERK and the PI3K-AKT signaling pathway.
[Uses]

KAL-21404358 is a ligand for target protein for pROTAC.
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