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1067654-70-9

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1067654-70-9 Structure

1067654-70-9 Structure
IdentificationBack Directory
[Name]

WK-298
[CAS]

1067654-70-9
[Synonyms]

WK-298
[Molecular Formula]

C35H38Cl2N6O
[MOL File]

1067654-70-9.mol
[Molecular Weight]

629.63
Chemical PropertiesBack Directory
[Boiling point ]

803.6±65.0 °C(Predicted)
[density ]

1.28±0.1 g/cm3(Predicted)
[pka]

14.33±0.30(Predicted)
Hazard InformationBack Directory
[Description]

WK-298 is a potent inhibitor of the MDM2/MDMX-p53 interaction.
[Uses]

WK298 is a potent inhibitor of the MDM2/MDMX-p53 interaction with good anti-tumor activity. WK298 can fully activate the p53 pathway by inhibiting the binding of MDM2 and MDMX to p53. The development of WK298 benefited from a deep understanding of the key elements of the p53-MDM2/MDMX interaction structure[1].
[References]

[1] Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction
1067654-70-9 suppliers list
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
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