| Identification | Back Directory | [Name]
5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE | [CAS]
107008-28-6 | [Synonyms]
RU-24969
RU 24969 HEMISUCCINATE
5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole hemisuccinate
5-METHOXY-3-(1,2,5,6-TETRAHYDRO-4-PYRIDINYL)-1H-INDOLE HEMISUCCINATE
5-Methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole succinate(2:1)
5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole succinate (2:1) salt
Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (1:1) | [Molecular Formula]
C18H22N2O5 | [MDL Number]
MFCD00673955 | [MOL File]
107008-28-6.mol | [Molecular Weight]
346.38 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
Solid | [color ]
Light yellow to yellow | [InChI]
InChI=1S/2C14H16N2O.C4H6O4/c2*1-17-11-2-3-14-12(8-11)13(9-16-14)10-4-6-15-7-5-10;5-3(6)1-2-4(7)8/h2*2-4,8-9,15-16H,5-7H2,1H3;1-2H2,(H,5,6)(H,7,8) | [InChIKey]
BNYJLRQAWCQJOM-UHFFFAOYSA-N | [SMILES]
N1C2C=CC(OC)=CC=2C(C2CCNCC=2)=C1.C(O)(=O)CCC(O)=O.N1C2C=CC(OC)=CC=2C(C2CCNCC=2)=C1 |
| Hazard Information | Back Directory | [Uses]
RU 24969 Succinate is a SR-1A and SR-1B, and moderate SR-2C agonist. 5-HT1B/1A agonist. Also, it is a well-established substrate for human serotonin transporter (SERT). | [Biological Activity]
Potent 5-HT 1A/1B and moderate 5-HT 2C agonist that may also release 5-HT. Centrally active following systemic administration. | [in vivo]
RU 24969 succinate (1 and 3 mg/kg; s.c., once) potentiates addictive agent-induced effects[2].
RU 24969 succinate (0.03-3.0 mg/kg; s.c., once) dose-dependently decreases water consumption in water deprived rats[4]. | Animal Model: | Male Wistar rats with cocaine injection[2] | | Dosage: | 1 and 3 mg/kg | | Administration: | Subcutaneous injection; 1 and 3 mg/kg, once | | Result: | Increased cocaine-induced elevation of nucleus accumbens (NAcc) dopamine DA levels and reduction of ventral tegmental area (VTA) GABA levels.
|
|
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
|