ChemicalBook--->CAS DataBase List--->1071638-38-4

1071638-38-4

1071638-38-4 Structure

1071638-38-4 Structure
IdentificationBack Directory
[Name]

MAC-13243
[CAS]

1071638-38-4
[Synonyms]

4-[[(4-Chlorophenyl)methyl]thio]-1-[2-(3,4-dimethoxyphenyl)ethyl]-1,2,3,6-tetrahydro-1,3,5-triazine hydrochloride (1:1)
[Molecular Formula]

C20H25Cl2N3O2S
[MDL Number]

MFCD18782745
[MOL File]

1071638-38-4.mol
[Molecular Weight]

442.402
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Powder
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

MAC13243, an antibacterial agent, is an inhibitor of bacterial lipoprotein targeting chaperone, LolA. MAC13243 is an antibacterial agent with Gram-negative selectivity[1][2].
[storage]

Store at -20°C
[References]

[1] Barker CA, et al. Degradation of MAC13243 and studies of the interaction of resulting thiourea compounds with the lipoprotein targeting chaperone LolA. Bioorg Med Chem Lett. 2013 Apr 15;23(8):2426-31. DOI:10.1016/j.bmcl.2013.02.005
[2] Pathania R, et al. Chemical genomics in Escherichia coli identifies an inhibitor of bacterial lipoprotein targeting. Nat Chem Biol. 2009 Nov;5(11):849-56. DOI:10.1038/nchembio.221
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