| Identification | Back Directory | [Name]
Ginkgolide J | [CAS]
107438-79-9 | [Synonyms]
BN 52024
J Ginkgoli
GINKGOLIDE J
7beta-hydroxyginkgolide a
GinkgolideA, 7-hydroxy-, (7β)-
Ginkgolide J, 98%, from Ginkgo biloba L.
9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-2,4,7b-trihydroxy-8-methyl-, (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)- | [Molecular Formula]
C20H24O10 | [MDL Number]
MFCD03093737 | [MOL File]
107438-79-9.mol | [Molecular Weight]
424.4 |
| Chemical Properties | Back Directory | [Melting point ]
>282oC (dec.) | [Boiling point ]
760.4±60.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
11.28±0.70(Predicted) | [color ]
White | [InChIKey]
LMEHVEUFNRJAAV-UZYDXDDANA-N | [SMILES]
C123C[C@]4([H])OC(=O)[C@@H](C)[C@]4(O)[C@]41C(O[C@]2([H])[C@H](O)[C@@H](C(C)(C)C)[C@]13[C@@H](O)C(=O)O[C@@]1([H])O4)=O |&1:2,7,9,11,14,16,18,23,24,29,r| | [LogP]
-0.680 (est) |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from ginkgo leaves. | [Uses]
Ginkgolide J is a terpene trilactone present in Ginkgo Biloba extracts, and used in the preparation of healthcare products including antioxidant agents. | [in vivo]
Ginkgolide J (100 μM) treatment reduces the apoptotic damage induced by serum deprivation (24h) or treatment with Staurosporine (200 nM, 24h) in cultured chick embryonic neurons[1]. |
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