| Identification | Back Directory | [Name]
ALPHA-PHENYL-1-(2-PHENYLETHYL)-4-PIPERIDINEMETHANOL | [CAS]
107703-78-6 | [Synonyms]
MDL 11
α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol
4-Piperidinemethanol, α-phenyl-1-(2-phenylethyl)- | [Molecular Formula]
C20H25NO | [MDL Number]
MFCD00864701 | [MOL File]
107703-78-6.mol | [Molecular Weight]
295.42 |
| Chemical Properties | Back Directory | [Melting point ]
125-128 °C | [Boiling point ]
434.2±20.0 °C(Predicted) | [density ]
1.084±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
DMSO: ≥8mg/mL | [form ]
powder | [pka]
14.13±0.20(Predicted) | [color ]
white to tan | [InChI]
1S/C21H27NO/c23-21(19-11-5-2-6-12-19)20-13-16-22(17-14-20)15-7-10-18-8-3-1-4-9-18/h1-6,8-9,11-12,20-21,23H,7,10,13-17H2 | [InChIKey]
CTDVLAJTGZQELM-UHFFFAOYSA-N | [SMILES]
OC(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3 |
| Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
50/53 | [Safety Statements ]
60-61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Acute 1 |
| Hazard Information | Back Directory | [Uses]
MDL 11,939 is a potent and selective SR-2 antagonist. It can also be used to treat psychological and brain disorders. | [Definition]
ChEBI: Phenyl-[1-(2-phenylethyl)-4-piperidinyl]methanol is a primary amine. | [Biological Activity]
Potent, selective and orally active 5-HT 2 receptor antagonist (K i values are 0.54 and 81.6 nM at 5-HT 2A and 5-HT 2C receptors respectively). | [in vivo]
Glemanserin (MDL11939) suppresses the induced increase in locomotor activity, behavioral sensitization and withdrawal symptoms in male mice[1]. | [storage]
Store at RT |
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BOC Sciences
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https://www.bocsci.com |
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