| Identification | Back Directory | [Name]
RS 87337 | [CAS]
107707-38-0 | [Synonyms]
RS 87337
N-(3,5-Dichlorophenyl)-4-(4-hydroxy-2-methoxyphenyl)-1-piperazinecarboxamidine
N-(3,5-Dichlorophenyl)-4-(4-hydroxy-2-methoxyphenyl)-1-piperazinecarbimide amide | [Molecular Formula]
C18H20Cl2N4O2 | [MOL File]
107707-38-0.mol | [Molecular Weight]
395.283 |
| Hazard Information | Back Directory | [Description]
RS 87337 is a chemically novel antiarrhythmic agent with an electrophysiologic profile characteristic of both class III and class Ia compounds. | [Uses]
RS-87337 is an orally active antiarrhythmic agent that increases the duration and the maximum rate of rise of cardiac muscle action potentials. RS-87337 is promising for research of antiarrhythmic and cardioprotective agents[1]. | [References]
[1] Dumez D, et al. Electrophysiologic, antiarrhythmic, and cardioprotective effects of N-[3,5 dichlorophenyl] 4-[4-hydroxy-2-methoxy-phenyl] piperazine carboxamidine dihydrochloride (RS-87337). J Cardiovasc Pharmacol. 1989 Aug;14(2):184-93. DOI:10.1097/00005344-198908000-00002 |
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