| Identification | Back Directory | [Name]
p-Terphenyl, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- | [CAS]
1080632-76-3 | [Synonyms]
2-dioxaborolan-2-yl)-
2-([1,1':4',1''-Terphenyl]-4-yl)
[1,1':4',1''-Terphenyl]-4-boronic acid pinacol ester
(1,1':4',1''-Terphenyl)-4-ylboronic Acid Pinacol Ester
p-Terphenyl, 4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-
4,4,5,5-Tetramethyl-2-[1,1':4',1''-terphenyl]-4-yl-1,3,2-dioxaborolane
2-([1,1':4',1"-terphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxabolorane
1,3,2-Dioxaborolane, 4,4,5,5-tetramethyl-2-[1,1':4',1''-terphenyl]-4-yl-
2-([1,1':4',1''-Terphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | [Molecular Formula]
C24H25BO2 | [MDL Number]
MFCD16294429 | [MOL File]
1080632-76-3.mol | [Molecular Weight]
356.265 |
| Chemical Properties | Back Directory | [Melting point ]
146 °C | [Boiling point ]
508.5±29.0 °C(Predicted) | [density ]
1.10 | [storage temp. ]
Inert atmosphere,2-8°C | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of [1,1':4',1''-terphenyl]-4-boronic acid pinacol ester from 4-bromo-p-terphenyl and bis(pinacolato)diboronic acid: 4-bromo-p-terphenyl (120 g, 388 mmol) was dissolved in 1.2 L of dimethylformamide (DMF) under nitrogen protection. Subsequently, bis(pinacolato)diboron (118 g, 466 mmol), 1,1'-bis(diphenylphosphino)ferric-palladium(II) dichloride (3.17 g, 3.88 mmol) and potassium acetate (114 g, 1,164 mmol) were added. The reaction mixture was heated to reflux at 150 °C for 4 hours. After completion of the reaction, the reaction solution was poured into water and the precipitate was collected by filtration. The resulting solid was dried in a vacuum oven. Finally, the crude product was separated and purified by fast column chromatography to afford [1,1':4',1''-terphenyl]-4-boronic acid pinacol ester (124 g, 90% yield). | [References]
[1] Patent: KR2015/117173, 2015, A. Location in patent: Paragraph 0284-0286
[2] Patent: US2017/331067, 2017, A1. Location in patent: Paragraph 0248-0251
[3] Patent: US2017/40550, 2017, A1. Location in patent: Paragraph 0083 |
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