| Identification | Back Directory | [Name]
probimane | [CAS]
108093-90-9 | [Synonyms]
MM-159
CS-2456
probimane
Bis(4-morpholinomethyl-3,5-dioxopiperazin-1-yl)propane
2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis(1-(4-morpholinylmethyl)- | [MDL Number]
MFCD30491873 |
| Hazard Information | Back Directory | [Description]
Probimane is anticancer agents. Pro is active against more categories of tumors both in vivo and in vitro, which in some circumstances may make it superior to the currently-used anticancer bisdioxopiperazines, including razoxane and MST-16. | [Uses]
Probimane (AT-2153) is a potent anticancer agent. Probimane is effective against mouse tumors S37, S180, Lewis lung carcinoma, L1210 and human pulmonary adenocarcinoma heterotransplanted into nude mice[1]. | [References]
[1] Lu DY, et al. [Distribution of 14C labeled at dioxopiperazine or methyl morpholine group of probimane by whole body autoradiography]. Zhongguo Yao Li Xue Bao. 1993 Mar;14(2):171-3. Chinese. PMID:8352014 |
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