| Identification | Back Directory | [Name]
Secretin (human) | [CAS]
108153-74-8 | [Synonyms]
Rg 1068
SECRETINHCL
SECRETIN, HUMAN
Unii-A0426J905j
Secretin (28-54), human
Secretin (human) USP/EP/BP
Secretin human, ≥97% (HPLC)
HSDGTFTSELSRLREGARLQRLLQGLV-NH3
HSDGTFTSELSRLREGARLQRLLQGLV-NH2
Secretin (pig), 15-L-glutamic acid-16-glycine-
Secretin (swine), 15-L-glutamic acid-16-glycine-
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH3
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 HUMAN
H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 hydrochloride salt
L-His-L-Ser-L-Asp-Gly-L-Thr-L-Phe-L-Thr-L-Ser-L-Glu-L-Leu-L-Ser-L-Arg-L-Leu-L-Arg-L-Glu-Gly-L-Ala-L-Arg-L-Leu-L-Gln-L-Arg-L-Leu-L-Leu-L-Gln-Gly-L-Leu-L-Val-NH2
L-Valinamide, L-histidyl-L-seryl-L-.alpha.-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-.alpha.-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-.alpha.-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl- | [EINECS(EC#)]
241-105-3 | [Molecular Formula]
C130H220N44O40 | [MDL Number]
MFCD00135670 | [MOL File]
108153-74-8.mol | [Molecular Weight]
3039.41 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
powder
| [color ]
White to off-white | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2 |
| Hazard Information | Back Directory | [Uses]
Stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma. | [Brand name]
SecretinKabi (KabiVitrum, Sweden). | [General Description]
Secretin is a gastrointestinal hormone and a neuropeptide. It is synthesized from a precursor protein and shares sequence homology with other secretin family proteins like glucagon and vasoactive intestinal peptide (VIP). | [Biochem/physiol Actions]
Secretin regulates the secretion of gastric acid and pancreatic bicarbonates. It serves as an antidiuretic hormone in the neurohypophysial-renal axis and participates in osmoregulation. Secretin mediates its function through the G-protein coupled secretin receptors. It regulates the pH of the duodenal by modulating gastric acid secretion. | [storage]
Store at -20°C |
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