| Identification | Back Directory | [Name]
9-(ethoxycarbonyl)-11H,12H-dibenzo[f,h]isoquino[2,1-b]isoquinolinium | [CAS]
108181-00-6 | [Synonyms]
DC_C66
9-(ethoxycarbonyl)-11H,12H-dibenzo[f,h]isoquino[2,1-b]isoquinolinium | [Molecular Formula]
C28H22NO2+ | [MDL Number]
MFCD05157417 | [MOL File]
108181-00-6.mol | [Molecular Weight]
404.49 |
| Hazard Information | Back Directory | [Uses]
DC_C66 is a cell-permeable, selective coactivator associated arginine methyltransferase 1 (CARM1) inhibitor with an IC50 of 1.8 μM. DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM), PRMT6 (IC50= 47μM), and PRMT5[1]. | [References]
[1] Ye F, et al. Identification of Novel Inhibitors against Coactivator Associated Arginine Methyltransferase 1 Based on Virtual Screening and Biological Assays. Biomed Res Int. 2016;2016:7086390. DOI:10.1155/2016/7086390 |
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