| Identification | Back Directory | [Name]
5-(piperazin-1-yl)pyridin-2-aMine | [CAS]
1082876-26-3 | [Synonyms]
Palbociclib-005
Palbociclib Impurity 44
5-(1-Piperazinyl)-2-pyridinamine
2-Amino-5-(1-piperazinyl)pyridine
5-(piperazin-1-yl)pyridin-2-aMine
5-Piperazin-1-yl-pyridin-2-ylamine
2-Pyridinamine, 5-(1-piperazinyl)-
Palbociclib impurity 6/5-(piperazin-1-yl)pyridin-2-amine | [Molecular Formula]
C9H14N4 | [MOL File]
1082876-26-3.mol | [Molecular Weight]
178.23 |
| Chemical Properties | Back Directory | [Boiling point ]
401.7±40.0 °C(Predicted) | [density ]
1.163±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
8.67±0.10(Predicted) | [color ]
Pale Brown to Light Brown | [InChI]
InChI=1S/C9H14N4/c10-9-2-1-8(7-12-9)13-5-3-11-4-6-13/h1-2,7,11H,3-6H2,(H2,10,12) | [InChIKey]
VBBGHNGROGZGHG-UHFFFAOYSA-N | [SMILES]
C1(N)=NC=C(N2CCNCC2)C=C1 |
| Hazard Information | Back Directory | [Uses]
5-?(1-?Piperazinyl)?-?2-?pyridinamine is a reagent used in the synthesis of anticancer agents. Also is an impurity of Palbociclib (P139900), an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. |
|
| Company Name: |
BePharm Ltd
|
| Telephone: |
400-685-9117 |
| Website: |
www.bepharm.com |
| Company Name: |
DoEasy Pharma Co., Ltd.
|
| Telephone: |
0571-0571-28806358 15397199029 |
| Website: |
http://www.deasypharma.com |
| Company Name: |
TOSUN PHARM
|
| Telephone: |
020-66392521-118 18922260391 |
| Website: |
www.toref.cn/ |
|