| Identification | Back Directory | [Name]
None | [CAS]
1083009-44-2 | [Synonyms]
5,5-difluoro-2,8-diiodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide | [Molecular Formula]
C19H18BF2I2N2 | [MOL File]
1083009-44-2.mol | [Molecular Weight]
576.98 |
| Hazard Information | Back Directory | [Description]
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres. | [Uses]
BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 μg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models[1]. | [References]
[1] Zou J, et al., BODIPY Derivatives for Photodynamic Therapy: Influence of Configuration versus Heavy Atom Effect. ACS Appl Mater Interfaces. 2017 Sep 27;9(38):32475-32481. DOI:10.1021/acsami.7b07569 | [Excitation / Emission Maximum]
649 nm/667 nm |
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