| Identification | Back Directory | [Name]
naltiazem | [CAS]
108383-95-5 | [Synonyms]
naltiazem
Naphtho[1,2-b][1,4]thiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S,3S)- | [Molecular Formula]
C26H28N2O4S | [MDL Number]
MFCD30738715 | [MOL File]
108383-95-5.mol | [Molecular Weight]
464.58 |
| Hazard Information | Back Directory | [Description]
Naltiazem, also known as RO-236152, is a calcium channel antagonist potentially for the treatment of arrhythmias, hypertension and myocardial infarction. | [Uses]
Naltiazem (Ro 23-6152) is a thiazepinone-type calcium antagonist. Naltiazem inhibits platelet aggregation in vitro and in vivo[1]. | [References]
[1] L A Sordahl, et al. In vivo inhibition of platelet aggregation and occlusive coronary thrombus formation by a new calcium antagonist (R023-6152). J Cardiovasc Pharmacol. 1991 Oct;18(4):504-10. DOI:10.1097/00005344-199110000-00005 |
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