| Identification | Back Directory | [Name]
2,5-Diazaspiro[3.4]octane-5-carboxylicacid-1,1-dimethylethylester | [CAS]
1086398-04-0 | [Synonyms]
5-Boc-2,5-diazaspiro[3.4]...
5-Boc-2,5-diaza-spiro[3.4]octane
tert-butyl 2,5-diazaspiro[3.4]octane-5-carboxylate
TERT-BUTYL 2,8-DIAZASPIRO[3.4]OCTANE-8-CARBOXYLATE
2,5-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester
2,8-diazaspiro[3.4]octane-8-carboxylic acid tert-butyl ester
tert-Butyl 2,8-Diazaspiro[3.4]octane-8-carboxylate hemioxalate
2,5-Diazaspiro[3.4]octane-5-carboxylicacid-1,1-dimethylethylester
2,5-Diazaspiro[3.4]octane-5-carboxylic acid tert-butyl ester oxalate | [Molecular Formula]
C11H20N2O2 | [MDL Number]
MFCD11501186 | [MOL File]
1086398-04-0.mol | [Molecular Weight]
212.29 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
solid | [Appearance]
Colorless to light yellow Solid-Liquid Mixture | [InChI]
1S/C11H20N2O2/c1-10(2,3)15-9(14)13-6-4-5-11(13)7-12-8-11/h12H,4-8H2,1-3H3 | [InChIKey]
XKASCTCECDLMSI-UHFFFAOYSA-N | [SMILES]
CC(C)(C)OC(=O)N1CCCC12CNC2 |
| Hazard Information | Back Directory | [Synthesis]
2,5-Diazaspiro[3.4]octane-5-carboxylicacid-1,1-dimethylethylester is a heterocyclic organic compound frequently used as a pharmaceutical intermediate. A few examples of 2,5-diazaspiro[3.4]octanes with N-Boc-protected
azetidine nitrogen were obtained by condensation of
N-Boc-azetidine-3-one with N-benzylbut-3-yn-1-amine elaborated for a streamlined synthesis of C(sp3)-rich N-heterospirocycles via visible-light-mediated Ir-photocatalyzed reactions[1]. | [References]
[1] Flodén, N.J.; Trowbridge, A.; Willcox, D.; Walton, S.M.; Kim, Y.; Gaunt, M.J. Streamlined Synthesis of C-Rich N-Heterospirocycles Enabled by Visible-Light-Mediated Photocatalysis. J. Am. Chem. Soc. 2019, 141, 8426–8430. DOI:10.1021/jacs.9b03372
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