| Identification | Back Directory | [Name]
Benzeneacetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-3,4-dihydroxy- | [CAS]
108729-21-1 | [Synonyms]
Influenza virus-IN-1
Benzeneacetamide, N-[2-(3,4-dihydroxyphenyl)ethyl]-3,4-dihydroxy- | [Molecular Formula]
C16H17NO5 | [MOL File]
108729-21-1.mol | [Molecular Weight]
303.31 |
| Hazard Information | Back Directory | [Uses]
Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 μM and CC50 of >200 μM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities[1]. | [References]
[1] Liao Y, et al. Synthesis and SARs of dopamine derivatives as potential inhibitors of influenza virus PAN endonuclease. Eur J Med Chem. 2020 Mar 1;189:112048. DOI:10.1016/j.ejmech.2020.112048 |
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