| Identification | Back Directory | [Name]
ilexsaponin B2 | [CAS]
108906-69-0 | [Synonyms]
ilexsaponin B2
product/154922
(3beta,20beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1→
2)-beta-D-xylopyranosyl)oxy]-19-hydroxy-urs-12-en-28-oic acid
Urs-12-en-28-oic acid, 3-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-β-D-xylopyranosyl)oxy]-19-hydroxy-, (3β,20β)-
(3beta,20beta)-3-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-2)-O-beta-D-glucopyranosyl-(1-2)-beta-D-xylopyranosyl)oxy]-19-hydroxy-urs-12-en-28-oic acid | [Molecular Formula]
C47H76O17 | [MDL Number]
MFCD32263352 | [MOL File]
108906-69-0.mol | [Molecular Weight]
913.1 |
| Hazard Information | Back Directory | [Uses]
Ilexsaponin B2 is a saponin isolated from the root of Ilex pubescens Hook. et Arn. Ilexsaponin B2 is a potent phosphodiesterase 5 (PDE5) and PDEI inhibitor with IC50 values of 48.8 μM and 477.5 μM, respectively[1]. | [IC 50]
PDE5: 48.8 μM (IC50); PDEI: 477.5 μM (IC50) | [References]
[1] Zichen Liu, et al. Rapid Screening of Potential Phosphodiesterase Inhibitors From the Roots of Ilex pubescens Hook. Et Arn. Using a Combination of Ultrafiltration and LC-MS. Evid Based Complement Alternat Med. 2017;2017:2749643. DOI:10.1155/2017/2749643 |
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