| Identification | Back Directory | [Name]
(3R,6E,10S)-6,10α-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione | [CAS]
108944-67-8 | [Synonyms]
Neocurdione
(3R,6E,10S)-6,10α-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione
(3R,6E,10S)-6,10-Dimethyl-3-(1-methylethyl)-6-cyclodecene-1,4-dione
6-Cyclodecene-1,4-dione,6,10-dimethyl-3-(1-methylethyl)-, (3R,6E,10S)- | [Molecular Formula]
C15H24O2 | [MDL Number]
MFCD01725514 | [MOL File]
108944-67-8.mol | [Molecular Weight]
236.35 |
| Hazard Information | Back Directory | [Hazard]
A poison by ingestion | [Uses]
Neocurdione is a hepatoprotective sesquiterpene isolated from Curcuma zedoaria rhizome. Neocurdione exerts potent effect on D-galactosamine- (D-Gain) and lipopolysaccharide- (LPS) induced acute liver injury in mice[1]. | [References]
[1] Carvalho FR, et al. Journal of Venomous Animals and Toxins including Tropical Diseases.On-line version ISSN 1678-9199
[2] Omer Abdalla Ahmed Hamdi,et al. Neuroprotective and Antioxidant Constituents from Curcuma zedoaria Rhizomes. Records of Natural Products . 2015, Vol. 9 Issue 3, p349-355. 8p. |
| Safety Data | Back Directory | [Safety Profile]
A poison by ingestion.
When heated to decomposition it emits
acrid smoke and irritating vapors. |
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