| Identification | Back Directory | [Name]
N-Caffeoyltryptophan | [CAS]
109163-69-1 | [Synonyms]
N-Caffeoyltryptophan
trans-Caffeoyl-L-tryptophan
trans-Caffeoyl-L-tryptophan sodium salt | [Molecular Formula]
C20H18N2O5 | [MOL File]
109163-69-1.mol | [Molecular Weight]
366.37 |
| Chemical Properties | Back Directory | [Boiling point ]
771.3±60.0 °C(Predicted) | [density ]
1.460±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3?+-.0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes[1]. | [Definition]
ChEBI: N-Caffeoyltryptophan is a N-acyl-amino acid. | [References]
[1] Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100. DOI:10.1016/j.phytochem.2022.113100
[2] Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47(7):1215-8. DOI:10.1016/s0031-9422(97)00754-1 |
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