| Identification | Back Directory | [Name]
Pyrrolo[1,2-a]pyrazine-2(1H)-acetic acid, hexahydro-α-3-pyridinyl-, 2-[3,5-bis(trifluoromethyl)phenyl]hydrazide, (αR,8aS)- | [CAS]
1092476-84-0 | [Synonyms]
Pyrrolo[1,2-a]pyrazine-2(1H)-acetic acid, hexahydro-α-3-pyridinyl-, 2-[3,5-bis(trifluoromethyl)phenyl]hydrazide, (αR,8aS)- | [Molecular Formula]
C22H23F6N5O | [MOL File]
1092476-84-0.mol | [Molecular Weight]
487.45 |
| Chemical Properties | Back Directory | [Boiling point ]
485.9±45.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
11.55±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
(αR,8aS)-GSK1614343 is the isomer of GSK1614343 (HY-113906). GSK1614343 is the potent antagonist of growth hormone secretagogues type 1a (GHS1a) receptors[1]. | [References]
[1] Perdonà E, et al. Pharmacological characterization of the ghrelin receptor antagonist, GSK1614343 in rat RC-4B/C cells natively expressing GHS type 1a receptors. Eur J Pharmacol. 2011;650(1):178-183. DOI:10.1016/j.ejphar.2010.10.042 |
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