| Identification | Back Directory | [Name]
LY 201409 | [CAS]
109306-94-7 | [Synonyms]
LY 201409
4-Amino-3,5-dimethyl-N-(2,6-dimethylphenyl)benzamide | [Molecular Formula]
C17H20N2O | [MDL Number]
MFCD00893556 | [MOL File]
109306-94-7.mol | [Molecular Weight]
268.35 |
| Hazard Information | Back Directory | [Description]
LY 201409 is a potent benzamide anticonvulsant. LY201409 antagonized maximal electroshock (MES)-induced seizures with ED50 values of 16.2 and 4.2 mg/kg after oral administration to mice and rats, respectively. | [Uses]
LY 201409 is an anticonvulsant compound that is an analog of LY-201116 (HY-114705) with improved metabolic activity. LY 201409 antagonizes maximal electroconvulsive-induced seizures, has mixed effects on seizures induced by multiple chemoconvulsants, and affects behavior and sleep in mice[1]. | [References]
[1] Robertson DW, et al. Pharmacology of LY201409, a potent benzamide anticonvulsant. Epilepsia. 1988 Nov-Dec;29(6):760-9. DOI:10.1111/j.1528-1157.1988.tb04232.x |
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