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109430-12-8

109430-12-8 Structure

109430-12-8 Structure
IdentificationBack Directory
[Name]

12(R)-HEPE
[CAS]

109430-12-8
[Synonyms]

12(R)-HEPE
MCRJLMXYVFDXLS-IHWYZUJNSA-N
12R-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
5,8,10,14,17-Eicosapentaenoic acid, 12-hydroxy-, (5Z,8Z,10E,12R,14Z,17Z)-
[Molecular Formula]

C20H30O3
[MDL Number]

MFCD00084833
[MOL File]

109430-12-8.mol
[Molecular Weight]

318.45
Chemical PropertiesBack Directory
[solubility ]

0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Danger
Hazard InformationBack Directory
[Description]

12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus. The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE (Catalog No. 34560).
[Uses]

12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S. purpuratus.1 The biological activity of 12(R)-HEPE has not been extensively documented, but may be similar to that of 12(R)-HETE.
[Definition]

ChEBI: 12R-HEPE is a HEPE.
[References]

[1] Masferrer, et al. 12(R)-Hydroxyeicosatetraenoic acid, an endogenous corneal arachidonate metabolite, lowers intraocular pressure in rabbits. Invest. Ophthalmol. Vis. Sci. 31(3), 535-539 (1990).
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