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Leucinostatin H is a novel peptide antibiotic isolated from Paecilomyces lilacinus. | [Uses]
Leucinostatin H is a polypeptide antibiotic discovered in Paecilomyces marquandii, characterized by a tertiary amine-oxide terminal group. Leucinostatin H exhibits inhibitory activity against Gram-positive bacteria, such as Bacillus subtilis, B. cereus, and Staphylococcus aureus (MIC 10-100 μg/mL). Leucinostatin H holds potential for research in anti-infective and plant disease control applications[1]. | [References]
[1] Radics L, et al. Leucinostatins H and K, two novel peptide antibiotics with tertiary amine-oxide terminal group from Paecilomyces marquandii isolation, structure and biological activity. J Antibiot (Tokyo). 1987 May;40(5):714-6. DOI:10.7164/antibiotics.40.714 |
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