| Identification | Back Directory | [Name]
6-BroMo-1,3-diMethyl-1H-i... | [CAS]
1095539-84-6 | [Synonyms]
6-BroMo-1,3-diMethyl-1H-i...
6-Bromo-1,3-dimethyl-indazole
1H-Indazole, 6-bromo-1,3-dimethyl-
6-Bromo-1,3-dimethyl-1H-indazole 95+% | [Molecular Formula]
C9H9BrN2 | [MDL Number]
MFCD12028626 | [MOL File]
1095539-84-6.mol | [Molecular Weight]
225.09 |
| Chemical Properties | Back Directory | [Boiling point ]
310.9±22.0 °C(Predicted) | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
1.38±0.50(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Synthesis]
1. 2-Acetyl-5-bromophenyl methanesulfonate was prepared according to the method described in International Application Publication No. WO 2005/090305 (Example 40a).
2. 2-acetyl-5-bromophenyl methanesulfonate was mixed with methylhydrazine and ammonium acetate and reacted under reflux conditions for 6 days to obtain 6-bromo-1,3-dimethyl-1H-indazole in 60% yield.
3. 6-Bromo-1,3-dimethyl-1H-indazole was dissolved in THF and treated with n-BuLi, followed by the passage of carbon dioxide gas, and the reaction afforded the target compound in a yield of 1.23 g in 60% yield. | [References]
[1] Patent: WO2008/65508, 2008, A1. Location in patent: Page/Page column 34 |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
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