ChemicalBook--->CAS DataBase List--->1096-84-0

1096-84-0

1096-84-0 Structure

1096-84-0 Structure
IdentificationBack Directory
[Name]

1,1'-METHYLENEDI-2-NAPHTHOL
[CAS]

1096-84-0
[Synonyms]

SQUOXIN
AKOS BBS-00002910
1,1’-methylenedi-2-naphtho
1,1'-METHYLENEDI-2-NAPHTHOL
1,1-METHYLENE-DI-2-NAPHTHOL
METHYLENE-1,1'-DI-2-NAPHTHOL
1,1'-METHYLENEBIS(2-NAPHTHOL)
Bis(2-hydroxy-1-naphtyl)methane
1,1-Methylene-di-2-naphthol,98%
BIS(2-HYDROXY-1-NAPHTHYL)METHANE
1,1'-Methylenebis(naphthalen-2-ol)
[1,1'-Methylenebisnaphthalene]-2,2'-diol
Bis(2-hydroxy-1-naphthyl)methane 1,1'-Methylenebis(2-naphthol)
[EINECS(EC#)]

214-145-4
[Molecular Formula]

C21H16O2
[MDL Number]

MFCD00046470
[MOL File]

1096-84-0.mol
[Molecular Weight]

300.35
Chemical PropertiesBack Directory
[Appearance]

LIGHT PINK TO LIGHT BROWN CRYSTALLINE POWDER
[Melting point ]

181-190 °C (dec.)(lit.)
[Boiling point ]

401.58°C (rough estimate)
[density ]

1.1027 (rough estimate)
[refractive index ]

1.5680 (estimate)
[form ]

powder to crystaline
[pka]

8.91±0.50(Predicted)
[color ]

White to Brown
[EPA Substance Registry System]

1,1-Methylenedi-2-naphthol (1096-84-0)
Hazard InformationBack Directory
[Chemical Properties]

LIGHT PINK TO LIGHT BROWN CRYSTALLINE POWDER
[Uses]

Squoxin (ST1859) is an antiamyloid agent that specifically binds to Aβ1-42 and prevents the aggregation and fibril formation of Aβ. Squoxin crosses the blood-brain barrier (BBB) and has anthelmintic activity and anti-inflammatory properties[1].
[References]

[1] Martin Bauer, et al. A positron emission tomography microdosing study with a potential antiamyloid drug in healthy volunteers and patients with Alzheimer's disease. Clin Pharmacol Ther. 2006 Sep;80(3):216-27. DOI:10.1016/j.clpt.2006.05.007
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[RTECS ]

QL4400000
[HS Code ]

2907.29.9000
[Toxicity]

mouse,LD50,intraperitoneal,1gm/kg (1000mg/kg),European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 381, 1978.
Spectrum DetailBack Directory
[Spectrum Detail]

1,1'-METHYLENEDI-2-NAPHTHOL(1096-84-0)MS
1,1'-METHYLENEDI-2-NAPHTHOL(1096-84-0)1HNMR
1,1'-METHYLENEDI-2-NAPHTHOL(1096-84-0)IR1
1,1'-METHYLENEDI-2-NAPHTHOL(1096-84-0)IR2
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