| Identification | Back Directory | [Name]
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- | [CAS]
1096144-06-7 | [Synonyms]
PST3 1a (NSC-753859)
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- | [Molecular Formula]
C32H33O6P | [MOL File]
1096144-06-7.mol | [Molecular Weight]
544.57 |
| Hazard Information | Back Directory | [Uses]
PST3.1a is a N-acetylglucosamine glycosyltransferase (MGAT5) inhibitor with the IC50 of 2 μM. PST3.1a inhibits glioblastoma-initiating cell invasiveness and proliferation[1]. | [References]
[1] Hassani Z, et al. Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation. Mol Cancer Res. 2017;15(10):1376-1387. DOI:10.1158/1541-7786.MCR-17-0120 |
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