| Identification | Back Directory | [Name]
D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL | [CAS]
109760-77-2 | [Synonyms]
D,L-ERYTHRO-PDMP
D,L-ERYTHRO-1-PHENYL-2-DECANOYLAMINO-3-MORPHOLINO-1-PROPANOL HCL
Decanamide, N-[(1R,2S)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-, rel- | [Molecular Formula]
C23H38N2O3 | [MDL Number]
MFCD08703011 | [MOL File]
109760-77-2.mol | [Molecular Weight]
390.56 |
| Hazard Information | Back Directory | [Uses]
D,L-erythro-PDMP is an erythro isomer of PDMP. D,L-erythro-PDMP causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2]. | [References]
[1] Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. DOI:10.1093/oxfordjournals.jbchem.a123236
[2] Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41. DOI:10.1016/0005-2760(95)00217-0 |
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