| Identification | Back Directory | [Name]
Ms-PEG8-Ms | [CAS]
109789-41-5 | [Synonyms]
Ms-PEG8-Ms 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diol, 1,20-dimethanesulfonate | [Molecular Formula]
C16H34O12S2 | [MDL Number]
MFCD30730377 | [MOL File]
109789-41-5.mol | [Molecular Weight]
482.56 |
| Hazard Information | Back Directory | [Description]
Ms-PEG8-Ms is a PEG linker with two mesyl groups. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
Ms-PEG7-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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