| Identification | Back Directory | [Name]
TAUROHYODEOXYCHOLIC ACID SODIUM SALT | [CAS]
110026-03-4 | [Synonyms]
SODIUM TAUROHYODEOXYCHOLATE
Sodium taurohyodeoxycholate hydrate
TAUROHYODEOXYCHOLIC ACID SODIUM SALT
Taurodeoxychloic Acid sodium hydrate
taurohyodeoxycholic acid sodium hydrate
5-BETA-CHOLANIC ACID-3-ALPHA, 6-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT | [EINECS(EC#)]
206-132-7 | [Molecular Formula]
C26H44NNaO6S | [MDL Number]
MFCD00271496 | [MOL File]
110026-03-4.mol | [Molecular Weight]
521.69 |
| Chemical Properties | Back Directory | [Melting point ]
168 °C (dec.)(lit.)
| [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
H2O: 0.1 g/mL, clear, colorless to very faintly yellow
| [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
A bile acid which stimulates the flow of bile salts, for potential treatment of Irritable Bile Syndrome. | [in vivo]
Taurodeoxycholate (0.5 mg/kg; i.v.; once) confers protection to C57BL/6N mice with sepsis, but does not protect TGR5 KO mice under sepsis[1]. | Animal Model: | C57BL/6N mice, Lipopolysaccharides (HY-D1056) injection model of sepsis[1] | | Dosage: | 0.5 mg/kg | | Administration: | Intravenous injection, 30 min or 24 h after LPS injection | | Result: | Improved the survival rate of mice with sepsis. Decreased liver and kidney damage in septic mice. Ameliorated systemic inflammation and normalized blood pressure in septic mice. |
| [IC 50]
Microbial Metabolite |
|
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
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