| Identification | Back Directory | [Name]
TOSAGESTIN | [CAS]
110072-15-6 | [Synonyms]
Org30659
Org-30659
Org 30659
TOSAGESTIN
19-Norpregna-4,15-dien-20-yn-3-one, 17-hydroxy-11-methylene-, (17α)- | [Molecular Formula]
C21H24O2 | [MDL Number]
MFCD09837742 | [MOL File]
110072-15-6.mol | [Molecular Weight]
308.41 |
| Hazard Information | Back Directory | [Uses]
Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells[1][2]. | [References]
[1] Schoonen WG, et al. Effects of two classes of progestagens, pregnane and 19-nortestosterone derivatives, on cell growth of human breast tumor cells: II. T47D cell lines. J Steroid Biochem Mol Biol. 1995;55(3-4):439-444. 、 DOI:10.1016/0960-0760(95)00216-2
[2] Obruca A, et al. Ovarian function during and after treatment with the new progestagen Org 30659. Fertil Steril. 2001;76(1):108-115. DOI:10.1016/s0015-0282(01)01824-6 |
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