| Identification | Back Directory | [Name]
4,4,4-Trifluoro-3-oxobutanenitrile | [CAS]
110234-68-9 | [Synonyms]
4,4,4-Trifluoro-3-oxobutanenitrile
4,4,4-Trifluoro-3-oxo-butyronitrile
Butanenitrile, 4,4,4-trifluoro-3-oxo- | [Molecular Formula]
C4H2F3NO | [MDL Number]
MFCD11099951 | [MOL File]
110234-68-9.mol | [Molecular Weight]
137.06 |
| Chemical Properties | Back Directory | [Boiling point ]
43 °C(Press: 2.5 Torr) | [density ]
1.350±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [pka]
2.74±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
4,4,4-Trifluoro-3-oxobutanenitrile (cas# 110234-68-9) is used as a reagent in the preparation of ((dimethoxyquinazolinyloxy)phenyl)urea derivatives as orally efficacious inhibitors of V-RAF murine sarcoma viral oncogene. Additionally, it is used as a reagent in preparation of orally active inhibitors of Brahma homolog (BRM)/SMARCA2 ATPase activity for treatment of Brahma related gene 1 (BRG1)/SMARCA4-mutant cancers. It is also used as a reagent in the synthesis of 2-(trifluoromethyl)nicotinic acid derivatives from fluorinated precursors. |
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