| Identification | Back Directory | [Name]
MDA 77 | [CAS]
1103774-21-5 | [Synonyms]
MDA 77
N-[(Z)-(6-methoxy-2-oxo-1-pentylindol-3-ylidene)amino]benzamide
Benzoic acid, (2Z)-2-(1,2-dihydro-6-methoxy-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide | [Molecular Formula]
C21H23N3O3 | [MOL File]
1103774-21-5.mol | [Molecular Weight]
365.43 |
| Chemical Properties | Back Directory | [Melting point ]
144.8 °C | [density ]
1.20±0.1 g/cm3(Predicted) | [solubility ]
DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: 0.25 mg/ml | [form ]
A crystalline solid | [pka]
10.21±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
MDA77 is a CB2 inverse agonist with an EC50 of 5.82 nM, showing selectivity for human CB2 and no activity on CB1[1]. | [References]
[1] Philippe Diaz, et al. 6-Methoxy-N-alkyl isatin acylhydrazone derivatives as a novel series of potent selective cannabinoid receptor 2 inverse agonists: design, synthesis, and binding mode prediction. J Med Chem. 2009 Jan 22;52(2):433-44. DOI:10.1021/jm801353p |
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| Company Name: |
LETOPHARM LIMITED
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| Telephone: |
+86-21-5821 5861 |
| Website: |
www.letopharm.com |
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