| Hazard Information | Back Directory | [Description]
L 858051 activates adenylate cyclase and inhibits glucose transport in rat adipocytes. | [Uses]
L 858051 is an analog of forskolin that activates adenylate cyclase while also having modulatory effects on intracellular cAMP levels, particularly enhancing the CNG current in cardiac myocytes. | [References]
[1] Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels DOI:10.1074/jbc.M405697200 |
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