| Identification | Back Directory | [Name]
1-(Methylnitrosoamino)-2-propanol | [CAS]
1104874-94-3 | [Synonyms]
MHP
Defensamide
Defensamide(MHP)
Methyl caprooyl tyrosinate
1-(Methylnitrosoamino)-2-propanol
L-Tyrosine, N-(1-oxohexyl)-, methyl ester
(S)-methyl 2-hexanamido-3-(4-hydroxyphenyl)propanoate | [Molecular Formula]
C16H23NO4 | [MDL Number]
MFCD31382170 | [MOL File]
1104874-94-3.mol | [Molecular Weight]
293.36 |
| Chemical Properties | Back Directory | [Boiling point ]
490.9±35.0 °C(Predicted) | [density ]
1.117±0.06 g/cm3(Predicted) | [solubility ]
DMSO:100.0(Max Conc. mg/mL);340.88(Max Conc. mM)
H2O:50.0(Max Conc. mg/mL);170.44(Max Conc. mM) | [form ]
Solid | [pka]
9.76±0.15(Predicted) | [color ]
White to off-white | [Cosmetics Ingredients Functions]
SKIN PROTECTING |
| Hazard Information | Back Directory | [Uses]
MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production. MHP (Methyl caprooyl tyrosinate) enhances antimicrobial defense and innate immunity[1]. | [IC 50]
SphK1 | [References]
[1] Jeong SK, et al. Sphingosine kinase 1 activation enhances epidermal innate immunity through sphingosine-1-phosphate stimulation of cathelicidin production. J Dermatol Sci. 2015 Sep;79(3):229-34. DOI:10.1016/j.jdermsci.2015.06.007 |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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Puripharm Co., Ltd.
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http://www.puriactives.com/ |
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