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1105038-73-0

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1105038-73-0 Structure

1105038-73-0 Structure
IdentificationBack Directory
[Name]

Abituzumab
[CAS]

1105038-73-0
[Synonyms]

Abituzumab
Abituzumab (anti-ITGAV)
Anti-Human CD51(Abituzumab)
Research Grade Abituzumab(DHC21901)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Abituzumab (DI17E6) is a humanised anti-integrin αV monoclonal antibody (IgG2 type). Abituzumab effectively reduces the phosphorylation of FAK, Akt and ERK. Abituzumab can be used in cancer research, particularly in prostate cancer[1].
[References]

[1] Jiang Y, et al. Abituzumab Targeting of αV-Class Integrins Inhibits Prostate Cancer Progression. Mol Cancer Res. 2017 Jul;15(7):875-883. DOI:10.1158/1541-7786.MCR-16-0447
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