| Identification | Back Directory | [Name]
FASORACETAM | [CAS]
110958-19-5 | [Synonyms]
LAM-105)
aka NS-105
110958-19-5
FASORACETAM
NS 105 (pharmaceutical)
Fasoracetam,NS-105,LAM-105
noopept fasoracetam powder
(5R)-5-(piperidine-1-carbonyl)-2-pyrrolidone
(5R)-5-piperidin-1-ylcarbonylpyrrolidin-2-one
(R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one
(5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one
(R)-1-[(5-Oxo-2-pyrrolidinyl)carbonyl]piperidine
2-Pyrrolidinone, 5-(1-piperidinylcarbonyl)-, (5R)-
(5R)-5-(Piperidine-1-Carbonyl)Pyrrolidin-2-One
(5R)-5-[Oxo-(1-Piperidyl)Methyl]-2-Pyrrolidinone | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C10H16N2O2 | [MDL Number]
MFCD00875708 | [MOL File]
110958-19-5.mol | [Molecular Weight]
196.25 |
| Chemical Properties | Back Directory | [Boiling point ]
456.8±38.0 °C(Predicted) | [density ]
1.181±0.06 g/cm3(Predicted) | [solubility ]
DMF: 20 mg/ml
DMSO: 5 mg/ml
Ethanol: 20 mg/mlPBS (pH 7.2): 10 mg/ml | [form ]
Solid | [pka]
15.45±0.40(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C10H16N2O2/c13-9-5-4-8(11-9)10(14)12-6-2-1-3-7-12/h8H,1-7H2,(H,11,13)/t8-/m1/s1 | [InChIKey]
GOWRRBABHQUJMX-MRVPVSSYSA-N | [SMILES]
N1[C@@H](C(N2CCCCC2)=O)CCC1=O |
| Hazard Information | Back Directory | [Description]
Fasoracetam (NS-105, 5-oxo-d-prolinepiperidinamide) is a member of the racetam family, a drug of the pyrrolidone class, and is currently considered a research chemical. The class is characterized by its nootropic (e.g., piracetam and fasoracetam), stimulating (e.g., oxiracetam), and anticonvulsant (e.g., levetiracetam) properties. Studies have shown promising results in its ability to counter and reverse the effects of Alzheimer's disease[1].
| [Uses]
Fasoracetam (NS 105) is the activator of metabotropic glutamate receptor (mGluR). Fasoracetam (NS 105) has the potential for the research of attention-deficit hyperactivity disorder (ADHD) and Alzheimer's disease (AD)[1][2]. | [Definition]
ChEBI: Fasoracetam is an amino acid amide. | [References]
[1] Bram Harmsen . “A Study of Fasoracetam’s Solid State Forms: A Potential Anti-Alzheimer Pharmaceutical.” Journal of pharmaceutical sciences 106 5 (2017): Pages 1317-1321.
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| Questions And Answer | Back Directory | [Structure]
Fasoracetam is a promising research chemical that is available in solid form in ambient conditions. Its chemical structure shows 2 amide functions that commonly take part in hydrogen bonding patterns. The carbonyl can serve as a hydrogen acceptor, whereas the amide can act as a hydrogen donor. Having multiple hydrogen bonding sites available could possibly lead to different packing arrangements. Furthermore, other racetam compounds have already shown a propensity toward the formation of multiple solid-state forms. |
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