| Identification | Back Directory | [Name]
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) | [CAS]
111112-18-6 | [Synonyms]
LY195448 HCl
UNII-BR0DFE3GF6
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) | [Molecular Formula]
C20H27ClN2O2 | [MOL File]
111112-18-6.mol | [Molecular Weight]
362.9 |
| Hazard Information | Back Directory | [Uses]
LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of "standard" side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor. | [References]
[1] Phase I clinical and pharmacokinetic study of LY 195448 |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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