| Identification | Back Directory | [Name]
7-Ethoxyrosmanol | [CAS]
111200-01-2 | [Synonyms]
7-Ethoxyrosmanol
rosmanol-9-ethylethe
Rosmanol-7-ethyl ether
Rosmannol-9-ethylether
2H-10,4a-(Epoxymethano)phenanthren-12-one, 9-ethoxy-1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10S,10aS)- | [Molecular Formula]
C22H30O5 | [MDL Number]
MFCD34469440 | [MOL File]
111200-01-2.mol | [Molecular Weight]
374.47 |
| Hazard Information | Back Directory | [Uses]
7-Ethoxyrosmanol is a phenolic diterpene that is isolated from Salvia chamelaeagnea. 7-Ethoxyrosmanol has antioxidant activity in vitro and antitumor effects on neuroblastoma cells. 7-Ethoxyrosmanol alleviates hyperglycemia-induced endothelial cell dysfunction via regulating FBXL7[1][2][3]. | [References]
[1] Ni J, et al. 7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression. J Bioenerg Biomembr. 2021 Oct;53(5):553-560. DOI:10.1007/s10863-021-09916-1
[2] Tabata K, et, al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov; 32(11): 4781-9. PMID:23155243
[3] Etsassala NGER, et, al. Investigation of In-Vitro Antioxidant and Electrochemical Activities of Isolated Compounds from Salvia chamelaeagnea P.J.Bergius Extract. Antioxidants (Basel). 2019 Apr 12; 8(4): 98. DOI:10.3390/antiox8040098 |
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