| Identification | Back Directory | [Name]
LB205 | [CAS]
1113025-86-7 | [Synonyms]
LB205
LB-205
(LB 205
Benzamide, 2-mercapto-N-[6-oxo-6-(3-pyridinylamino)hexyl]- | [Molecular Formula]
C18H21N3O2S | [MOL File]
1113025-86-7.mol | [Molecular Weight]
343.44 |
| Hazard Information | Back Directory | [Uses]
LB-205 is a pan-histone deacetylase inhibitor (HDACi). LB-205 can be used for the research of acute traumatic brain injury[1][2]. | [References]
[1] Lu J, et, al. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52. DOI:10.1073/pnas.1308950110
[2] Lu J, et, al. Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5. DOI:10.1073/pnas.1119181109 |
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