| Identification | Back Directory | [Name]
sperabillin A | [CAS]
111337-86-1 | [Synonyms]
sperabillin A
Sperabillin A (free base)
L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadien-1-yl]amino]- | [Molecular Formula]
C15H27N5O3 | [MDL Number]
MFCD00911700 | [MOL File]
111337-86-1.mol | [Molecular Weight]
325.41 |
| Hazard Information | Back Directory | [Description]
Sperabillin A (free base) is an antibacterial antibiotic with potent in vivo activity, isolated from Pseudomonas fluorescens YK-437. | [Uses]
Sperabillin A is an antibacterial agent against gram-positive and gram-negative bacteria. Sperabillin A shows strong inhibition of human umbilical vein endothelial (HUVE) cell proliferation. Sperabillin A also shows anti-tumor acfivity against B16 melanoma in mouse[1]. | [References]
[1] Hida T, et al. Chemistry and anti-tumor activity of sperabillin polymers. Chem Pharm Bull (Tokyo). 1993 May;41(5):889-93. DOI:10.1248/cpb.41.889 |
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